MACROPHAGE INHIBITOR CLODRONATE ENHANCES LIVER TRANSDUCTION OF LENTIVIRAL BUT NOT ADENO-ASSOCIATED VIRAL VECTORS OR MRNA LIPID NANOPARTICLES IN NEONATAL AND JUVENILE MICE

Macrophage Inhibitor Clodronate Enhances Liver Transduction of Lentiviral but Not Adeno-Associated Viral Vectors or mRNA Lipid Nanoparticles in Neonatal and Juvenile Mice

Recently approved adeno-associated viral (AAV) vectors for liver monogenic diseases haemophilia A and B are exemplifying the success of liver-directed viral gene therapy.In parallel, additional gene therapy strategies are rapidly emerging A Dynamic and Adaptive Selection Radar Tracking Method Based on Information Entropy to overcome some inherent A

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The Influence of Abiotic Environment and Connectivity on the Distribution of Diversity in an Andean Fish Fluvial Network

The distribution of Andean freshwater fishes is the result of the interaction of historical and contemporary factors such as basin geomorphology and the physicochemical characteristics of water bodies.Dramatic changes along river networks due to waterfalls or dams generate abrupt changes in longitudinal slopes that function as ecological barriers t

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